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Orthomolecular Medicine is involved with the use of dietary measures including air, water, food, and nutritional supplements to maintain health and treat disease. Dr. Linus Pauling the founder of orthomolecular medicine defines it this way: "The preservation of good health and the treatment of disease by varying the concentration in the human (and canine) body of substances that are normally present in the body and are required for health."

Veterinarians that practice orthomolecular medicine attempt to raise the levels of all essential nutrients in the animals body up to at least a minimum level for health maintenance and disease prevention but ideally far above that level into a range that will provide optimal health.

Orthomolecular medicine is also concerned with reducing the levels of food toxins and nutrients that may be in excess i.e. simple sugars, heavy metals, and artificial chemical additives.

Orthomolecular medicine involves itself with the use of bitters, enzymes, fiber, fatty acids, amino acids, anti-oxidants, beneficial bacterial, natural hormones and mega doses of vitamins and minerals in order to prevent and treat disease and promote optimal wellness.